We attempt to create a future molecular scaffold, with which highly efficient and selective chloride ion transportation will be feasible. Supramolecular chemistry derived polyamide protein mimetics (foldamers) were developed with various structural and functional properties. We aim to utilize such constructs for the transportation of ions through membranes. The synthesis of foldamers will be carried out in a highly efficient continuous flow peptide synthetizer.
Founded in 08/2015, the group is focused on biologically relevant molecules and macromolecular complexes, where intermoleculer interactions play a pivotal role in manifesting biological function. We are particularly interested in molecular level understanding of structure, function and mechanisms of membrane active compounds. Our aim is to study and design natural and nature-mimicking species which can be further developed in biomedical applications targeting organism-specific membranes.
Our research group was established in 2009 with the aim of connecting the traditional colloid chemistry with the new challenges in biology and medicine. The primary task of the Research Group is the synthesis of nanosized systems for medical applications including the modification of nanostructures, their characterization from the atomic level up to the µm range, optimization for biological and medical applications, and preliminary toxicity investigation in cell cultures and small animals.