Rapid, simple, and efficient deprotection of benzyl/benzylidene protected carbohydrates by utilization of flow chemistry

Author
Abstract

A rapid, simple, and efficient deprotection procedure for the deprotection of benzyl- and/or benzylidene protected carbohydrates is described utilizing a continuous flow hydrogenation reactor. The method tolerates both acid- and base sensitive functional groups. The high efficiency, simple work-up, and short reaction time should make this method appealing to researchers working in the fields of carbohydrate chemistry and total synthesis. (C) 2011 Elsevier Ltd. All rights reserved.

Year of Publication
2011
Journal
Tetrahedron Letters
Volume
52
Number of Pages
1839–1841
ISSN Number
0040-4039
URL
https://doi.org/10.1016/j.tetlet.2010.12.109
DOI
10.1016/j.tetlet.2010.12.109
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