Thickness determination of ultrathin poly(acrylic acid) shell on γ-Fe2O3 nanocore via small-angle scattering

TitleThickness determination of ultrathin poly(acrylic acid) shell on γ-Fe2O3 nanocore via small-angle scattering
Publication TypeJournal Article
Year of Publication2018
AuthorsLi, H, Wang, K, Tuo, X, Almásy, L, Tian, Q, Sun, G, Henderson, MJulian, Li, Q, Wacha, A, Courtois, J, Yan, M
JournalMaterials Chemistry and Physics
Volume204
Pagination236 - 242
ISSN0254-0584
KeywordsCore-shell nanoparticles, Small-angle X-ray and neutron scattering, Ultra-thin polymer coatings
Abstract

Core-shell polymer coated superparamagnetic nanoparticles are critical tools in bio-nanotechnology, in which the soft and thin polymeric coatings play a key role in their stabilization, surface functionality and biocompatibility. Standard characterization tools, such as Transmission Electron Microscopy are indispensable for the morphological characterization of the metal-containing core but they cannot clearly discriminate between core and shell components. Dynamic Light Scattering can only overestimate the shell thickness by measuring the particle hydrodynamic diameter. Here, we describe Small-Angle X-ray Scattering and Small-Angle Neutron Scattering as tools to study poly (acrylic) acid coated gamma iron oxide superparamagnetic nanoparticles dispersed in aqueous medium. Our results show that Small-Angle Scattering techniques offers in situ and sensitive measurements of the “stealth” polymer coatings which cannot be accurately detected by other techniques. The Small Angle Scattering approach presented in this work is applicable for analysis of core-shell organic/inorganic hybrid nanoparticles systems for a broad range of applications.

URLhttp://www.sciencedirect.com/science/article/pii/S0254058417308362
DOI10.1016/j.matchemphys.2017.10.047