|Title||A simple, efficient, and selective deuteration via a flow chemistry approach|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Mándity, IM, Martinek, TA, Darvas, F, Fülöp, F|
A simple and efficient deuteration methodology has been established for a wide variety of substrates using a continuous flow hydrogenation reactor. The described procedure is many times faster (1 mg min(-1)) compared to literature methods and the purity of the crude product can be as high as 99%. The deuterium Source is D2O, the consumption of which is very low. (C) 2009 Elsevier Ltd. All rights reserved.