|Title||Five unique compounds: Xyloketals from mangrove fungus Xylaria sp. from the South China Sea coast|
|Publication Type||Journal Article|
|Year of Publication||2001|
|Authors||Lin, Y, Wu, X, Feng, S, Jiang, G, Luo, J, Zhou, S, Vrijmoed, LLP, Jones, EBG, Krohn, K, Steingröver, K, Zsila, F|
|Journal||Journal of Organic Chemistry|
|Pagination||6252 - 6256|
Five unique metabolites, xyloketals A (1), B (2), C (3), D (4), and E (5), and the known 6 were isolated from mangrove fungus Xylaria sp. (no. 2508), obtained from the South China Sea. The structures of these compounds were elucidated by spectroscopic and X-ray diffraction experiments. Xyloketal A is a ketal compound with a C3 symmetry and xyloketals B-E are its analogues. It was found that xytoketal C slowly rearranged to xytoketal B in DMSO-d6 solution at room temperature. Xyloketal A exhibited the activity of inhibiting acetylcholine esterase.