Five unique compounds: Xyloketals from mangrove fungus Xylaria sp. from the South China Sea coast

TitleFive unique compounds: Xyloketals from mangrove fungus Xylaria sp. from the South China Sea coast
Publication TypeJournal Article
Year of Publication2001
AuthorsLin, Y, Wu, X, Feng, S, Jiang, G, Luo, J, Zhou, S, Vrijmoed, LLP, Jones, EBG, Krohn, K, Steingröver, K, Zsila, F
JournalJournal of Organic Chemistry
Volume66
Issue19
Pagination6252 - 6256
Date Published2001
Abstract

Five unique metabolites, xyloketals A (1), B (2), C (3), D (4), and E (5), and the known 6 were isolated from mangrove fungus Xylaria sp. (no. 2508), obtained from the South China Sea. The structures of these compounds were elucidated by spectroscopic and X-ray diffraction experiments. Xyloketal A is a ketal compound with a C3 symmetry and xyloketals B-E are its analogues. It was found that xytoketal C slowly rearranged to xytoketal B in DMSO-d6 solution at room temperature. Xyloketal A exhibited the activity of inhibiting acetylcholine esterase.

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